Most probably you have to allow live trading . . .
Tools > Options > Expert Advisor Tick "Allow live trading", if you are using an EA you should also do the same in the EA Properties.

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I use the MT4 platform from Pro Brokerage. The simplest operation, OrderSend(Symbol(),OP_SELL,1,Bid,3,0,0,"",MAGICMA,0,Red), returns 133(trading is disabled) all the time.
Who could help on this?
Thank you.