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forex calculation mode vs cfd calculation mode MT4 platform

As I am new on forex trading. can anyone explain what the difference between forex calculation mode vs CFD calculation mode on MT4 platform I have a very simple question, like for 1 pound bet(1 mini lot) in spread bet account(UK) I get 100 pound for 100 pip profit( cfd calculation mode) , where as

MT4 supported windows OS

Can I installed MT4 on windows server 2012 R2( Server PC) Operating System